DMAE / Dimethylaminoethenol Review: Information & Benefits

DMAE is an acronym for dimethylaminoethenol. It is a substance produced naturally in the brain and is a mild nervous system stimulant. DMAE can cross the blood-brain barrier, where it is converted into choline as needed by the body. Choline is B-complex vitamin necessary for proper brain function.

DMAE is said to have a number of health benefits. Because it is an antioxidant, it may prevent or reverse damage to DNA caused by free radicals, and it appears to have the ability to counteract the effects of environmental stressors such as pollution, cigarette smoke, physical exercise and chemicals. DMAE plays a role in strengthening the immune system, and it appears to guard against cardiovascular disease and other degenerative conditions.

As a precursor to choline, DMAE has a number of benefits to the brain as well. It can ease the symptoms of hyperactivity and attention deficit, helping to improve attention span and learning in people with ADD or ADHD. In one study, students given DMAE supplements for six weeks showed significant improvement in their ability to concentrate while listening to lectures and taking tests.

Some animal studies suggest that DMAE may also increase life span, probably due to its effects on the immune system and brain function. It appears to further facilitate brain activity by helping to increase the production of neurotransmitters and other chemicals related to cognitive function.

In studies, people reported feeling more alert and able to concentrate within hours of taking DMAE supplements. As mentioned earlier, the effectiveness of DMAE on brain chemistry is thought to be due to its ability to cross the blood-brain barrier before being converted into choline.

It appears to reduce apathy in depressed subjects, and it may also be effective in alleviating symptoms of anxiety. "Age spots" were also less common in subjects who took DMAE supplements, and it is possible that DMAE not only prevents these spots from developing but may also eliminate or lighten existing age spots. It may help to make skin firmer and more youthful in appearance as well.

DMAE can also help the body deal with dietary stressors like hydrogenated oils and rancid fats that contribute to oxidation and the production of free radicals. It removes these free radicals before they are able to cause damage in the body at the cellular level. A study of the ability of DMAE to reverse the effects of excessive alcohol intake showed that after six weeks, DMAE supplements appeared to prevent hangovers and eliminate alcohol-related depression. Subjects also reported higher energy levels and increased motivation.

Because DMAE can cause anxiety or a restless feeling, it is a good idea to start with a low dose of 50 to 150 mg per day. Many people find this amount to be sufficient, though doses of 200 to 600 mg per day are sometimes recommended.

DMAE supplements should be taken early in the day to avoid insomnia. Other side effects may include muscle tension or headaches, though most side effects can be eliminated by lowering the dosage. People who suffer from epilepsy or bipolar disorder should not use DMAE without medical supervision.

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